Rotation will be needed with Champions League football back this year, but who comes in as the regular starter alongside Hojbjerg remains to be seen.
Joe Rodon and Japhet Tanganga replacements
Both central defenders are leaving on loan moves away from Tottenham and that could leave Conte with just five options. Davinson Sanchez, Cristian Romero, Eric Dier and Clement Lenglet will all be fighting for starting spots in the three central positions while Ben Davies is expected to provide cover where necessary.
But injuries to just two of them at the same time could leave Conte in a pickle he would rather avoid. Marc Guehi has been tipped as an option for Tottenham all summer and, once Rodon and Tanganga leave on loan, Tottenham may need to make their move.