There have also been reports of people in the buildings where the blaze is taking place.
Properties in the area have now been evacuated and a welfare unit has been established.
Restaurants and offices above where the fire started have now been impacted by the blaze.
Support has been provided by crew members from Greater Manchester Fire Service and Lancashire Fire Service.
Residents have been advised to keep all doors and windows shut and avoid areas where the blaze is raging.
According to West Yorkshire Fire & Rescue, the blaze broke out at a property in La Perla, Burlees House, Hangingstones Road.
Gas and electricity support has also been requested.
Hebden Bridge Town Hall is now open to anyone affected by the blaze.
West Yorkshire Fire & Rescue also revealed four properties on either side of the blaze are now involved.